Jamie shares her experience living with Hashimoto's disease, an autoimmune condition affecting the thyroid. She talks about how her symptoms, such as fatigue and joint pain, were often dismissed as normal, leading to a delayed diagnosis. We talk about how difficult it was for her to find a treatment for her narcolepsy, due to the lack of diversity in clinical trials. Jamie also shares how medication shortages are affecting her and others, and how dire the situation is in the US. Jamie is an advocate for more education about chronic illnesses, particularly in recognizing symptoms in children, and she highlights her work in increasing the understanding of autoimmune diseases.

The song that Jamie chose is Fight Song by Rachel Platten.

Crohn's Disease is extremely unpredictable, and very hard to manage. Natalie was diagnosed with it just as her career was about to start. She didn't let it stop her; she decided to follow her dream of becoming a TV anchor no matter what. It wasn't that easy. She recounts episodes of great struggle and how difficult it is to manage the pain linked to Crohn's. Though the disease has shaped who she is, it does not define her.

The song Natalie chose is Swim by Jack's Mannequin.